EIF3B anticorps
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- Antigène Voir toutes EIF3B Anticorps
- EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF3B est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- EIF3B Antibody detects endogenous levels of total EIF3B
- Réactivité croisée
- Humain, Souris
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human EIF3B
- Isotype
- IgG
- Top Product
- Discover our top product EIF3B Anticorps primaire
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- Indications d'application
- WB 1:1000-3000 IHC 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
- Autre désignation
- EIF3B (EIF3B Produits)
- Synonymes
- anticorps EIF3-ETA, anticorps EIF3-P110, anticorps EIF3-P116, anticorps EIF3S9, anticorps PRT1, anticorps AL033316, anticorps AL033334, anticorps AL033369, anticorps AW208965, anticorps D5Wsu45e, anticorps Eif3s9, anticorps eif3-eta, anticorps eif3-p110, anticorps eif3-p116, anticorps eif3s9, anticorps prt1, anticorps ATEIF3B-2, anticorps EIF3B, anticorps EUKARYOTIC TRANSLATION INITIATION FACTOR 3B, anticorps F18A17.30, anticorps F18A17_30, anticorps eukaryotic translation initiation factor 3B-2, anticorps DDBDRAFT_0218512, anticorps DDBDRAFT_0233929, anticorps DDB_0218512, anticorps DDB_0233929, anticorps eIF-3-eta, anticorps eif3b, anticorps wu:fc17c01, anticorps GB10123, anticorps eIF3b, anticorps AO090005000892, anticorps CaO19.6584, anticorps eIF3 p90, anticorps eukaryotic translation initiation factor 3 subunit B, anticorps eukaryotic translation initiation factor 3, subunit B, anticorps eukaryotic translation initiation factor 3B-2, anticorps eukaryotic initiation factor, anticorps RNA recognition motif-containing protein RRM, anticorps eukaryotic translation initiation factor 3b, anticorps eukaryotic translation initiation factor 3 subunit B L homeolog, anticorps eukaryotic translation initiation factor 3, subunit Ba, anticorps eukaryotic translation initiation factor 3 subunit 9, anticorps translation initiation factor eIF-3 subunit 9, anticorps Eukaryotic translation initiation factor 3 subunit B, anticorps translation initiation factor eIF3 subunit b, anticorps EIF3B, anticorps Eif3b, anticorps eif3b, anticorps EIF3B-2, anticorps eIF3s9, anticorps eif3B, anticorps eif3b.L, anticorps eif3ba, anticorps LOC410100, anticorps eIF3-S9, anticorps AOR_1_1564174, anticorps VDBG_02490, anticorps PGTG_13070, anticorps Tsp_02250, anticorps eif-3.B, anticorps PRT1
- Sujet
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Description: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3B
- Poids moléculaire
- 116 kDa
- ID gène
- 8662
- UniProt
- P55884
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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