GCKR anticorps (Internal Region)

N° du produit ABIN6261914

Détail du produit anti-GCKR anticorps

Antigène: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCKR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: GCKR Antibody detects endogenous levels of total GCKR.

Homologie: Pig,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GCKR, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GCKR

Antigène: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Autre désignation: GCKR (GCKR Produits)

Synonymes: anticorps FGQTL5, anticorps GKRP, anticorps GLRE, anticorps gckr, anticorps glucokinase regulator, anticorps glucokinase regulatory protein, anticorps glucokinase regulator L homeolog, anticorps GCKR, anticorps Gckr, anticorps gckr.L

Sujet:

Description: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Gene: GCKR

Poids moléculaire: 68kDa

ID gène: 2646

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus