IFNAR1 anticorps (Internal Region)

N° du produit ABIN6262471

Détail du produit anti-IFNAR1 anticorps

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: IFNAR1 Antibody detects endogenous levels of total IFNAR1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IFNAR1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR1 (IFNAR1 Produits)

Synonymes: anticorps ifnar1, anticorps IFNAR1, anticorps CD118, anticorps Ifar, anticorps Ifnar, anticorps Ifrc, anticorps Infar, anticorps AVP, anticorps IFN-alpha-REC, anticorps IFNAR, anticorps IFNBR, anticorps IFRC, anticorps IFN-R-1, anticorps interferon alpha and beta receptor subunit 1, anticorps interferon-alpha/beta receptor alpha chain-like, anticorps interferon (alpha and beta) receptor 1, anticorps interferon alpha/beta receptor 1, anticorps IFNAR1, anticorps ifnar1, anticorps Ifnar1, anticorps LOC609830

Sujet:

Description: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

Gene: IFNAR1

Poids moléculaire: 63kDa

ID gène: 3454

UniProt: P17181

Pathways: Signalistation JAK/STAT, Hepatitis C