SCN9A anticorps (Internal Region)

N° du produit ABIN6263503

Détail du produit anti-SCN9A anticorps

Antigène: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN9A est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: Nav1.7 Antibody detects endogenous levels of total Nav1.7.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Nav1.7, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SCN9A

Antigène: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Autre désignation: SCN9A (SCN9A Produits)

Synonymes: anticorps SCN9A, anticorps DKFZp459G084, anticorps Nav1.7, anticorps PN1, anticorps mKIAA4197, anticorps Scn2a, anticorps ETHA, anticorps FEB3B, anticorps GEFSP7, anticorps NE-NA, anticorps NENA, anticorps SFNP, anticorps sodium channel, voltage-gated, type IX, alpha subunit, anticorps sodium voltage-gated channel alpha subunit 9, anticorps sodium channel protein type 9 subunit alpha, anticorps sodium channel, voltage-gated, type IX, alpha, anticorps SCN9A, anticorps LOC100016648, anticorps Scn9a

Sujet:

Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).

Gene: SCN9A

Poids moléculaire: 220kDa

ID gène: 6335

UniProt: Q15858