SCN9A anticorps (AA 1751-1946) (Biotin)
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- Antigène Voir toutes SCN9A Anticorps
- SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
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Épitope
- AA 1751-1946
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SCN9A est conjugé à/à la Biotin
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Antibody Array (AA)
- Specificité
- Detects ~230 kDa. No cross-reactivity against other Nav channels.
- Réactivité croisée
- Hamster, Humain, Souris, Rat
- Purification
- Protein G Purified
- Immunogène
- Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7
- Clone
- N68-6 (Formerly S68-6)
- Isotype
- IgG1
- Top Product
- Discover our top product SCN9A Anticorps primaire
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- Indications d'application
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Commentaires
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1 μg/ml of ABIN2483097 was sufficient for detection of Nav1.7 in 10 μg of HEK-293 cell lysate transiently expressing Nav1.7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- Antigène
- SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
- Autre désignation
- Nav1.7 (SCN9A Produits)
- Synonymes
- anticorps SCN9A, anticorps DKFZp459G084, anticorps Nav1.7, anticorps PN1, anticorps mKIAA4197, anticorps Scn2a, anticorps ETHA, anticorps FEB3B, anticorps GEFSP7, anticorps NE-NA, anticorps NENA, anticorps SFNP, anticorps sodium channel, voltage-gated, type IX, alpha subunit, anticorps sodium voltage-gated channel alpha subunit 9, anticorps sodium channel protein type 9 subunit alpha, anticorps sodium channel, voltage-gated, type IX, alpha, anticorps SCN9A, anticorps LOC100016648, anticorps Scn9a
- Sujet
- Nav1.7 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.7 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.7 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals (1-3).
- ID gène
- 6335
- NCBI Accession
- NP_002968
- UniProt
- Q15858
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