PAX6 anticorps (Internal Region)

N° du produit ABIN6277765

Détail du produit anti-PAX6 anticorps

Antigène: PAX6 (Paired Box 6 (PAX6))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: PAX6 Antibody detects endogenous levels of total PAX6.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PAX6, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PAX6

Antigène: PAX6 (Paired Box 6 (PAX6))

Autre désignation: PAX6 (PAX6 Produits)

Synonymes: anticorps pax6, anticorps an2, anticorps mgda, anticorps wagr, anticorps pax-6, anticorps pax6a, anticorps xpax6, anticorps XLPAX6, anticorps MGC52531, anticorps PAX-6, anticorps AN, anticorps AN2, anticorps D11S812E, anticorps MGDA, anticorps WAGR, anticorps Pax-6, anticorps pax6b, anticorps 1500038E17Rik, anticorps AEY11, anticorps Dey, anticorps Gsfaey11, anticorps Sey, anticorps PAXZF-A, anticorps Pax6.1, anticorps cb280, anticorps fc20e07, anticorps pax-a, anticorps pax[zf-a], anticorps paxzfa, anticorps wu:fc20e07, anticorps zfpax-6a, anticorps zfpax-6b, anticorps paired box 6, anticorps paired box 6 L homeolog, anticorps paired box 6 S homeolog, anticorps paired box 6a, anticorps PAX6, anticorps pax6, anticorps Pax6, anticorps pax6.L, anticorps pax6.S, anticorps pax6a

Sujet:

Description: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Gene: PAX6

Poids moléculaire: 47 kDa

ID gène: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis