PNKP anticorps (Internal Region)

N° du produit ABIN6264320

Détail du produit anti-PNKP anticorps

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: PNKP Antibody detects endogenous levels of total PNKP.

Homologie: Pig,Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PNKP, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP (PNKP Produits)

Synonymes: anticorps EIEE10, anticorps MCSZ, anticorps PNK, anticorps Tb06.28P18.320, anticorps 21.m03011, anticorps 1810009G08Rik, anticorps polynucleotide kinase 3'-phosphatase, anticorps hypothetical protein, anticorps polynucleotide kinase 3'- phosphatase, anticorps PNKP, anticorps Pnkp, anticorps Tc00.1047053507017.50, anticorps Tc00.1047053505807.190, anticorps Tb927.6.1580, anticorps BBOV_IV000690, anticorps CC1G_05202, anticorps PGTG_20262, anticorps PGTG_18987, anticorps pnkp.S, anticorps pnkp

Sujet:

Description: Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.

Gene: PNKP

Poids moléculaire: 60kDa

ID gène: 11284

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation