DLG4 anticorps (C-Term)
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- Antigène Voir toutes DLG4 Anticorps
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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Épitope
- C-Term
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Reactivité
- Rat, Souris, Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DLG4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- PSD95 Antibody detects endogenous levels of total PSD95.
- Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human PSD95, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DLG4 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
- Autre désignation
- DLG4 (DLG4 Produits)
- Synonymes
- anticorps 11, anticorps CG1725, anticorps CG1730, anticorps CPD, anticorps DLG, anticorps DLG-A, anticorps Discs-large, anticorps Dlg, anticorps Dlg-A, anticorps Dlg1, anticorps DlgA, anticorps Dmel\\CG1725, anticorps Drodlg, anticorps PSD95, anticorps SAP97, anticorps anon-EST:Posey93, anticorps anon-WO03040301.258, anticorps anon-WO03040301.260, anticorps anon-WO03040301.268, anticorps d. lg.-1, anticorps dlg, anticorps dlg-1, anticorps dlg-A, anticorps dlgA, anticorps dlgS97, anticorps l(1)10Bf, anticorps l(1)G0276, anticorps l(1)G0342, anticorps l(1)G0456, anticorps l(1)G19, anticorps l(1)L11, anticorps l(1)bwn, anticorps l(1)d.lg-1, anticorps l(1)d.lg.-1, anticorps l(1)discs large, anticorps l(1)dlg, anticorps l(1)dlg-1, anticorps l(1)dlg1, anticorps l(1)l.pr.-2, anticorps l(1)lpr-2, anticorps misb, anticorps dlgh4, anticorps psd95, anticorps sap90, anticorps sap-90, anticorps LLGL1, anticorps Dlgh4, anticorps PSD-95, anticorps SAP90, anticorps SAP90A, anticorps Sap90, anticorps SAP-90, anticorps DLG4, anticorps discs large 1, anticorps discs, large homolog 4, anticorps discs large MAGUK scaffold protein 4, anticorps discs, large homolog 4b (Drosophila), anticorps discs, large homolog 4 (Drosophila), anticorps dlg1, anticorps dlg4, anticorps DLG4, anticorps dlg4b, anticorps Dlg4
- Sujet
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Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.
Gene: DLG4
- Poids moléculaire
- 105 kDa
- ID gène
- 1742
- UniProt
- P78352
- Pathways
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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