RALB anticorps (C-Term)

N° du produit ABIN6264625

Détail du produit anti-RALB anticorps

Antigène: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RALB est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RALB Antibody detects endogenous levels of total RALB.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RALB, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RALB

Antigène: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Autre désignation: RALB (Ralb Produits)

Synonymes: anticorps dRalb, anticorps 5730472O18Rik, anticorps Ral B, anticorps ralb, anticorps xralb, anticorps zgc:100801, anticorps KRAS2, anticorps k-ras, anticorps RAS like proto-oncogene B, anticorps v-ral simian leukemia viral oncogene B, anticorps v-ral simian leukemia viral oncogene homolog B L homeolog, anticorps v-ral simian leukemia viral oncogene homolog Ba (ras related), anticorps v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein), anticorps RALB, anticorps Ralb, anticorps ralb.L, anticorps ralba, anticorps ralb

Sujet:

Description: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).

Gene: RALB

Poids moléculaire: 23 kDa

ID gène: 5899

UniProt: P11234

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events