POLR2G anticorps (Internal Region)

N° du produit ABIN6264819

Détail du produit anti-POLR2G anticorps

Antigène: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2G est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RPB7 Antibody detects endogenous levels of total RPB7.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RPB7, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur POLR2G

Antigène: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Autre désignation: POLR2G (POLR2G Produits)

Synonymes: anticorps RPB19, anticorps RPB7, anticorps hRPB19, anticorps hsRPB7, anticorps Rpb7, anticorps POLR2G, anticorps 2410046K11Rik, anticorps A230108L04Rik, anticorps C76415, anticorps RBP7, anticorps Rpo2-7l, anticorps RNA polymerase II subunit G, anticorps polymerase (RNA) II (DNA directed) polypeptide G, anticorps polymerase (RNA) II (DNA directed) polypeptide G L homeolog, anticorps POLR2G, anticorps Polr2g, anticorps polr2g, anticorps polr2g.L

Sujet:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Gene: POLR2G

Poids moléculaire: 19 kDa

ID gène: 5436

UniProt: P62487

Pathways: Regulatory RNA Pathways