SCG5 anticorps (Internal Region)

N° du produit ABIN6264938

Détail du produit anti-SCG5 anticorps

Antigène: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCG5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: SCG5 Antibody detects endogenous levels of total SCG5.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SCG5, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SCG5

Antigène: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Autre désignation: SCG5 (SCG5 Produits)

Synonymes: anticorps zgc:73132, anticorps sgne1, anticorps MGC145087, anticorps 7B2, anticorps AI325031, anticorps Sgne-1, anticorps Sgne1, anticorps P7B2, anticorps SGNE1, anticorps SgV, anticorps secretogranin V, anticorps scg5, anticorps SCG5, anticorps Scg5

Sujet:

Description: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Gene: SCG5

Poids moléculaire: 24 kDa

ID gène: 6447

UniProt: P05408