SFRP1 anticorps (Internal Region)
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- Antigène Voir toutes SFRP1 Anticorps
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SFRP1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- SFRP1 Antibody detects endogenous levels of total SFRP1.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human SFRP1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SFRP1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
- Autre désignation
- SFRP1 (SFRP1 Produits)
- Synonymes
- anticorps FRP, anticorps FRP-1, anticorps FRP1, anticorps FrzA, anticorps SARP2, anticorps 2210415K03Rik, anticorps AW011917, anticorps AW107218, anticorps AW742929, anticorps sFRP-1, anticorps CSFRP1, anticorps SFRP1, anticorps XfrzA, anticorps frp, anticorps frp-1, anticorps frp1, anticorps frzA, anticorps sarp2, anticorps sfrp1, anticorps LOC100231868, anticorps Srfp1a, anticorps wu:fd19b09, anticorps secreted frizzled related protein 1, anticorps secreted frizzled-related protein 1, anticorps Secreted frizzled-related protein 1, anticorps secreted frizzled-related protein 1a, anticorps secreted frizzled-related protein 1b, anticorps SFRP1, anticorps Sfrp1, anticorps sfrp1, anticorps sfrp1a, anticorps sfrp1b
- Sujet
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Description: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Gene: SFRP1
- Poids moléculaire
- 35 kDa
- ID gène
- 6422
- UniProt
- Q8N474
- Pathways
- Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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