TFCP2L1 anticorps (N-Term)

N° du produit ABIN6265527

Détail du produit anti-TFCP2L1 anticorps

Antigène: TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFCP2L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: TF2L1 Antibody detects endogenous levels of total TF2L1.

Homologie: Pig,Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TF2L1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TFCP2L1

Antigène: TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))

Autre désignation: TFCP2L1 (TFCP2L1 Produits)

Synonymes: anticorps CRTR1, anticorps LBP-9, anticorps LBP9, anticorps 1810030F05Rik, anticorps 4932442M07Rik, anticorps AA575098, anticorps Cp2l1, anticorps Crtr-1, anticorps D930018N21Rik, anticorps Tcfcp2l1, anticorps zgc:91796, anticorps TFCP2L1, anticorps lbp-9, anticorps crtr1, anticorps lbp9, anticorps tfcp2l1, anticorps tfcp2l1a, anticorps transcription factor CP2 like 1, anticorps transcription factor CP2-like protein 1, anticorps transcription factor CP2-like 1, anticorps transcription factor CP2-like 1 L homeolog, anticorps TFCP2L1, anticorps LOC100078599, anticorps Tfcp2l1, anticorps tfcp2l1, anticorps tfcp2l1.L

Sujet:

Description: Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity). Required for normal duct development in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity). Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity). Modulates the placental expression of CYP11A1 (PubMed:10644752).

Gene: TFCP2L1

Poids moléculaire: 55 kDa

ID gène: 29842

UniProt: Q9NZI6