TOLLIP anticorps (Internal Region)

N° du produit ABIN6265668

Détail du produit anti-TOLLIP anticorps

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOLLIP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TOLLIP Antibody detects endogenous levels of total TOLLIP.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TOLLIP, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TOLLIP

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Autre désignation: TOLLIP (TOLLIP Produits)

Synonymes: anticorps IL-1RAcPIP, anticorps 4930403G24Rik, anticorps 4931428G15Rik, anticorps fk22a02, anticorps im:7145391, anticorps wu:fk22a02, anticorps zgc:76985, anticorps TOLLIP, anticorps GB17961, anticorps tollip, anticorps tollip1, anticorps tollipa, anticorps TOLIP, anticorps toll interacting protein, anticorps toll-interacting protein, anticorps toll-interacting protein-like, anticorps toll interacting protein L homeolog, anticorps toll interacting protein S homeolog, anticorps Toll-interleukine I receptor interacting protein I, anticorps TOLLIP, anticorps Tollip, anticorps tollip, anticorps LOC552034, anticorps LOC100169858, anticorps tollip.L, anticorps tollip.S, anticorps LOC100136122

Sujet:

Description: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

Gene: TOLLIP

Poids moléculaire: 30kDa

ID gène: 54472

UniProt: Q9H0E2