BMP2 anticorps (C-Term)

N° du produit ABIN6283442

Détail du produit anti-BMP2 anticorps

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Épitope: AA 341-390, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: BMP-2 is a protein encoded by the BMP2 gene which is approximately 44,7 kDa. BMP-2 is secreted into the extracellular space. It is involved in apoptotic pathways, PEDF induced signalling, the GPCR pathway and ERK signalling. This protein is a secreted ligand of the TGF-beta superfamily of proteins. It binds various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. It is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. BMP-2 is expressed in the bone, muscle, bone marrow, nervous system and lung. Mutations in the BMP2 gene may result in Cauda Equina syndrome. STJ97346 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of BMP-2 protein.

Specificité: BMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.

Attributs du produit: Rabbit polyclonal to BMP-2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human BMP-2.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000

Commentaires:

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur BMP2

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: BMP-2 (BMP2 Produits)

Synonymes: anticorps BDA2, anticorps BMP2A, anticorps AI467020, anticorps Bmp2a, anticorps BMP-2, anticorps xBMP-2, anticorps xbmp2, anticorps BMP2, anticorps bmp2a, anticorps bmp2, anticorps wu:fc59d09, anticorps bone morphogenetic protein 2, anticorps bone morphogenetic protein 2 L homeolog, anticorps Bone morphogenetic protein 2, anticorps bone morphogenetic protein 2a, anticorps BMP2, anticorps Bmp2, anticorps bmp2.L, anticorps bmp2, anticorps bmp2a

ID gène: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation