NOS2 anticorps (AA 90-170)
-
- Antigène Voir toutes NOS2 Anticorps
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
-
Épitope
- AA 90-170
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp NOS2 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Fonction
- NOS2 is a protein encoded by the NOS2 gene which is approximately 131,1 kDa. NOS2 is localised to the cytoplasm. It is involved in arginine biosynthesis, toxoplasmosis, G-beta gamma signalling and PEDF induced signalling. It is a nitric oxide synthase messenger molecule with diverse functions throughout the body. In macrophages, it mediates tumoricidal and bactericidal actions and is also involved in inflammation by enhancing the synthesis of proinflammatory mediators such as IL6 and IL8. NOS2 is expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Mutations in the NOS2 gene may result in borderline leprosy and Peyronie's disease. STJ94534 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of NOS2 protein.
- Specificité
- NOS2 Polyclonal Antibody detects endogenous levels of NOS2 protein.
- Attributs du produit
- Rabbit polyclonal to NOS2.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human NOS2 around the non-phosphorylation site of Y151.
- Isotype
- IgG
- Top Product
- Discover our top product NOS2 Anticorps primaire
-
-
- Indications d'application
-
WB 1:500-1:2000
ELISA 1:10000 - Commentaires
-
Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- Antigène
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
- Autre désignation
- NOS2 (NOS2 Produits)
- Synonymes
- anticorps HEP-NOS, anticorps INOS, anticorps NOS, anticorps NOS2A, anticorps NOS-II, anticorps Nos-2, anticorps Nos2a, anticorps i-NOS, anticorps iNOS, anticorps iNos, anticorps NOS2a, anticorps NOS2, anticorps BmNOS2, anticorps Nsl, anticorps nos2, anticorps nitric oxide synthase 2, anticorps nitric oxide synthase 2, inducible, anticorps inducible nitric oxide synthase, anticorps inducible nitric-oxide synthase, anticorps nanos C2HC-type zinc finger 2, anticorps NOS2, anticorps Nos2, anticorps nos2, anticorps LOC396821, anticorps NANOS2
- Poids moléculaire
- 131 kDa
- ID gène
- 4843
- UniProt
- P35228
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-