ATP6V1H anticorps (Internal Region)

N° du produit ABIN6287269

Détail du produit anti-ATP6V1H anticorps

Antigène: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Épitope: AA 310-390, Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1H est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55,9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.

Specificité: V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.

Attributs du produit: Rabbit polyclonal to V-ATPase H.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human V-ATPase H

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Commentaires:

Widely expressed.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur ATP6V1H

Antigène: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Autre désignation: V-ATPase H (ATP6V1H Produits)

Synonymes: anticorps MSTP042, anticorps NBP1, anticorps SFD, anticorps SFDalpha, anticorps SFDbeta, anticorps VMA13, anticorps V-ATPASE, anticorps 0710001F19Rik, anticorps AU022349, anticorps CGI-11, anticorps chunp6890, anticorps ATPase H+ transporting V1 subunit H, anticorps ATPase, H+ transporting, lysosomal V1 subunit H, anticorps ATP6V1H, anticorps Atp6v1h, anticorps atp6v1h

Poids moléculaire: 55 kDa

ID gène: 51606

UniProt: Q9UI12

Pathways: Transition Metal Ion Homeostasis, Proton Transport