ATP6V1H anticorps (C-Term)

N° du produit ABIN651375

Détail du produit anti-ATP6V1H anticorps

Antigène: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Épitope: AA 400-426, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1H est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ATP6V1H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human ATP6V1H.

Clone: RB25984

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ATP6V1H

Antigène: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Autre désignation: ATP6V1H (ATP6V1H Produits)

Synonymes: anticorps MSTP042, anticorps NBP1, anticorps SFD, anticorps SFDalpha, anticorps SFDbeta, anticorps VMA13, anticorps V-ATPASE, anticorps 0710001F19Rik, anticorps AU022349, anticorps CGI-11, anticorps chunp6890, anticorps ATPase H+ transporting V1 subunit H, anticorps ATPase, H+ transporting, lysosomal V1 subunit H, anticorps ATP6V1H, anticorps Atp6v1h, anticorps atp6v1h

Sujet: ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase.

Poids moléculaire: 55883

ID gène: 51606

NCBI Accession: NP_057025, NP_998784, NP_998785

UniProt: Q9UI12

Pathways: Transition Metal Ion Homeostasis, Proton Transport