KIF7 anticorps

N° du produit ABIN6288850

Détail du produit anti-KIF7 anticorps

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIF7 est non-conjugé

Application: Immunofluorescence (IF)

Fonction: Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.

Specificité: The antibody detects endogenous Kif 7 proteins.

Attributs du produit: Mouse monoclonal to Kif 7.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide

Clone: 3F8

Isotype: IgG1

Information d'application

Indications d'application: IHC 1:200

Commentaires:

Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur KIF7

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Autre désignation: Kif 7 (KIF7 Produits)

Synonymes: anticorps KIF7, anticorps DDBDRAFT_0204609, anticorps DDBDRAFT_0206583, anticorps DDB_0204609, anticorps DDB_0206583, anticorps ACLS, anticorps HLS2, anticorps JBTS12, anticorps UNQ340, anticorps cos2, anticorps costal2, anticorps kinesin family member 7, anticorps KIF7, anticorps kif7, anticorps Kif7

ID gène: 374654

UniProt: Q2M1P5

Pathways: Signalisation Hedgehog