CLDN14 anticorps

N° du produit ABIN6290241

Détail du produit anti-CLDN14 anticorps

Antigène: CLDN14 (Claudin 14 (CLDN14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLDN14 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CLDN14

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Liver, kidney, Also found in ear

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur CLDN14

Antigène: CLDN14 (Claudin 14 (CLDN14))

Autre désignation: CLDN14 (CLDN14 Produits)

Synonymes: anticorps claudin-14, anticorps CLDN14, anticorps DFNB29, anticorps AI851731, anticorps claudin 14 L homeolog, anticorps claudin 14, anticorps cldn14.L, anticorps CLDN14, anticorps Cldn14

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 25.699 kDa

ID gène: 23562

UniProt: O95500

Pathways: Cell-Cell Junction Organization, Hepatitis C