JAM3 anticorps

N° du produit ABIN6290538

Détail du produit anti-JAM3 anticorps

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAM3 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human JAM3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Highest expression in placenta, brain and kidney, Significant expression is detected on platelets, Expressed in intestinal mucosa cells, Expressed in the vascular endothelium, Found in serum (at protein level), Also detected in the synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis or ostearthritis (at protein level)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur JAM3

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Autre désignation: JAM3 (JAM3 Produits)

Synonymes: anticorps JAM3, anticorps jam3, anticorps sr:nyz155, anticorps wu:fb30h11, anticorps wu:fc08c06, anticorps wu:fc13e04, anticorps wu:fc25g11, anticorps jamc.2, anticorps 1110002N23Rik, anticorps JAM-3, anticorps JAM-C, anticorps Jcam3, anticorps JAM-2, anticorps JAMC, anticorps junctional adhesion molecule 3, anticorps junctional adhesion molecule 3b, anticorps junctional adhesion molecule 3a, anticorps junction adhesion molecule 3, anticorps JAM3, anticorps jam3b, anticorps jam3a, anticorps Jam3

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 35.02 kDa

ID gène: 83700

UniProt: Q9BX67