CCNDBP1 anticorps
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- Antigène Voir toutes CCNDBP1 Anticorps
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCNDBP1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human CCNDBP1
- Isotype
- IgG
- Top Product
- Discover our top product CCNDBP1 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Commentaires
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Ubiquitously expressed, Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- Autre désignation
- CCNDBP1 (CCNDBP1 Produits)
- Synonymes
- anticorps CCNDBP1, anticorps dip1, anticorps gcip, anticorps DIP1, anticorps GCIP, anticorps HHM, anticorps AU022347, anticorps Maid, anticorps SECC-8, anticorps SSEC-8, anticorps cyclin D1 binding protein 1, anticorps cyclin D-type binding-protein 1, anticorps CCNDBP1, anticorps ccndbp1, anticorps Ccndbp1
- Sujet
- This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
- Poids moléculaire
- 40.262 kDa
- ID gène
- 23582
- UniProt
- O95273
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