SPRY2 anticorps
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- Antigène Voir toutes SPRY2 Anticorps
- SPRY2 (Sprouty Homolog 2 (SPRY2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPRY2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human SPRY2
- Isotype
- IgG
- Top Product
- Discover our top product SPRY2 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- Autre désignation
- SPRY2 (SPRY2 Produits)
- Synonymes
- anticorps wu:fk66h11, anticorps wu:fk93e11, anticorps zgc:110440, anticorps hspry2, anticorps xspry2, anticorps sprouty2, anticorps Xsprouty2, anticorps sprouty-2, anticorps Xtsprouty2, anticorps hSPRY2, anticorps sprouty RTK signaling antagonist 2, anticorps sprouty RTK signaling antagonist 2 S homeolog, anticorps sprouty homolog 2 (Drosophila), anticorps spry2, anticorps SPRY2, anticorps spry2.S, anticorps Spry2
- Sujet
- This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
- Poids moléculaire
- 34.688 kDa
- ID gène
- 10253
- UniProt
- O43597
- Pathways
- EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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