FNTA anticorps (Center)

N° du produit ABIN6295422

Détail du produit anti-FNTA anticorps

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Épitope: AA 88-118, Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNTA est non-conjugé

Application: Veuillez nous consulter SVP

Fonction: Rabbit Anti-FNTA (Center) Antibody

Immunogène: This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur FNTA

Antigène: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Autre désignation: FNTA (FNTA Produits)

Synonymes: anticorps ATFTA, anticorps FARNESYLTRANSFERASE A, anticorps FARNESYLTRANSFERASE SUBUNIT A, anticorps PFT/PGGT-IALPHA, anticorps PLP, anticorps PLURIPETALA, anticorps farnesyltransferase A, anticorps FPTA, anticorps PGGT1A, anticorps PTAR2, anticorps PFAS, anticorps FTA, anticorps farnesyltransferase A, anticorps farnesyltransferase, CAAX box, alpha, anticorps FTA, anticorps FNTA, anticorps Fnta

Sujet:

Target Description: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

Gene Symbol: FNTA

ID gène: 2339

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling