IGLV1-51 anticorps

N° du produit ABIN6296841

Détail du produit anti-IGLV1-51 anticorps

Antigène: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGLV1-51 est non-conjugé

Application: Immunohistochemistry (IHC)

Fonction: Mouse anti-Human Lambda Light Chain Antibody Cocktail [IHC only]

Specificité: Cell surface, cytoplasmic and secreted

Purification: Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda light chain antibody cocktail.

Immunogène: Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda light chain antibody cocktail.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur IGLV1-51

Antigène: IGLV1-51 (Immunoglobulin lambda Variable 1-51 (IGLV1-51))

Autre désignation: Immunoglobulin lambda variable 1-51 (IGLV1-51 Produits)

Synonymes: anticorps IGLV151, anticorps V1-19, anticorps immunoglobulin lambda variable 1-51, anticorps IGLV1-51

Sujet:

Target Description: This antibody cocktail is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Lambda light chain antibody is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGLV1-51///IGLC1

ID gène: 3535

UniProt: P01701, P0CG04