XRCC5 anticorps (AA 323-338)

N° du produit ABIN636304

Détail du produit anti-XRCC5 anticorps

Antigène: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Épitope: AA 323-338

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRCC5 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): This antibodys immunogen shares 100 % sequence identity with the human, Mouse, muroidea and rat homologs

Purification: Affinity chromatography purified

Immunogène: Ku80 antibody was raised in rabbit using AA 323-338 [FSKVDEEQMKYKSEGK] of the 80 kDa Ku80 protein as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur XRCC5

Antigène: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Autre désignation: Ku80 (XRCC5 Produits)

Synonymes: anticorps AI314015, anticorps Ku80, anticorps Ku86, anticorps Kup80, anticorps KARP-1, anticorps KARP1, anticorps KU80, anticorps KUB2, anticorps NFIV, anticorps xrcc5-a, anticorps XRCC5, anticorps X-ray repair cross complementing 5, anticorps X-ray repair complementing defective repair in Chinese hamster cells 5, anticorps X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog, anticorps XRCC5, anticorps Xrcc5, anticorps xrcc5.L

Sujet: The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends.

Pathways: Réparation de l'ADN