Presenilin 2 anticorps

N° du produit ABIN636358

Cet anticorps Chèvre Polyclonal détecte spécifiquement Presenilin 2 dans . Il présente une réactivité envers Mammifères.

Aperçu rapide pour Presenilin 2 anticorps (ABIN636358)

Antigène: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Reactivité: Mammifères

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Presenilin 2 est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-Presenilin 2 anticorps

Purification: Purified

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur Presenilin 2

Antigène: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Autre désignation: Presenilin 2

Sujet: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway