BAK1 anticorps

N° du produit ABIN645850

Cet anticorps Chèvre not_set détecte spécifiquement BAK1. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour BAK1 anticorps (ABIN645850)

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivité: Souris, Rat

Hôte: Chèvre

Conjugué: Cet anticorp BAK1 est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-BAK1 anticorps

Specificité: The goat Anti-BAK1 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Réactivité croisée: Souris, Rat (Rattus)

Attributs du produit: Goat Anti-BAK1

Immunogène: Peptide with sequence C-ASGQGPGPPRQE, from the N Terminus of the protein sequence according to NP_001179, was used as immunogen.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Stock: -20 °C

Détails sur BAK1

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Autre désignation: BAK1

Sujet: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

NCBI Accession: NP_001179

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response