ADAM17 anticorps (Domain 17)

N° du produit ABIN647517

Cet anticorps anti-ADAM17 not_set Chèvre (ABIN647517) détecte spécifiquement ADAM17. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour ADAM17 anticorps (Domain 17) (ABIN647517)

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivité: Rat, Souris

Hôte: Chèvre

Conjugué: Cet anticorp ADAM17 est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-ADAM17 anticorps

Épitope: Domain 17

Specificité: The ADAM17 goat antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.

Réactivité croisée: Souris, Rat (Rattus)

Attributs du produit: Goat Anti-ADAM17 / TACE, with HRP-conjugated secondary antibody

Immunogène: Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3. was used as immunogen.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: Supplied as 100 µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Stock: -20 °C

Détails sur ADAM17

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Autre désignation: ADAM17 / TACE

Sujet: ADAM17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), snake venom-like protease. Tumor necrosis factor beta (TNFbeta), also known as lymphotoxin, is a pleiotropic cytokine that has a molecular weight of 25 kDa. TNFalpha, also known as cachetin, is a 17 kDa cytokine that binds to the same receptors, producing an array of effects similar to those of TNFbeta. TNFbeta and TNFalpha share 30% amino acid homology and have similar biological activities. TNFbeta is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFalpha is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFbeta and TNFalpha can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFalpha converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFalpha precursor to release soluble TNFalpha.

NCBI Accession: NP_003174

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus