CLCN7 anticorps (C-Term)

N° du produit ABIN655808

Détail du produit anti-CLCN7 anticorps

Antigène: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Épitope: AA 692-720, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLCN7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CLCN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-720 amino acids from the C-terminal region of human CLCN7.

Clone: RB31756

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CLCN7 (ABIN655808)

Yoshimoto, Morita, Matsubara, Mitsuyasu, Imai, Kajioka, Yoneda, Ito, Hirofuji, Nakamura, Hirata: "Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone." dans: International journal of oncology, Vol. 48, Issue 3, pp. 1258-70, (2016) (PubMed).

Détails sur CLCN7

Antigène: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Autre désignation: CLCN7 (CLCN7 Produits)

Synonymes: anticorps CLC-7, anticorps CLC7, anticorps OPTA2, anticorps OPTB4, anticorps PPP1R63, anticorps AA409691, anticorps AW538136, anticorps ClC-7, anticorps D17Wsu51e, anticorps MGC80627, anticorps im:7155923, anticorps zgc:153490, anticorps CLCN7, anticorps chloride voltage-gated channel 7, anticorps chloride channel, voltage-sensitive 7, anticorps chloride channel, voltage-sensitive 7 L homeolog, anticorps chloride channel 7, anticorps chloride channel protein 7, anticorps CLCN7, anticorps Clcn7, anticorps clcn7.L, anticorps clcn7, anticorps CpipJ_CPIJ008618

Sujet: The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Poids moléculaire: 88679

ID gène: 1186

NCBI Accession: NP_001107803, NP_001278

UniProt: P51798