Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This Maspin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human Maspin.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Zhang, Liu, Shi, Qiao, Zeng, Feng, Deng, Liu, Wu: "Maspin impairs the function of endothelial cells: an implying pathway of preeclampsia." dans: BMC pregnancy and childbirth, Vol. 17, Issue 1, pp. 328, (2018) (PubMed).
Shi, Chen, Liu, Qiao, Liu, Gong, Li, Du, Liu, Tang, Cao, Wu: "Decitabine improves the clinical manifestations of rats with l-NAME-induced pre-eclampsia: a potential approach to studying pre-eclampsia." dans: Hypertension in pregnancy, pp. 1-10, (2015) (PubMed).
Antigène
SERPINB5
(serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
anticorps 1110036M19Rik, anticorps AI462524, anticorps AI646751, anticorps Maspin, anticorps PI-5, anticorps Spi7, anticorps ovalbumin, anticorps PI5, anticorps maspin, anticorps Pi5, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 5, anticorps serpin family B member 5, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog, anticorps Serpinb5, anticorps SERPINB5, anticorps serpinb5.S
Sujet
SERPINB5 is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.