FCN3 anticorps (C-Term)
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- Antigène Voir toutes FCN3 Anticorps
- FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))
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Épitope
- AA 214-243, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FCN3 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This FCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human FCN3.
- Clone
- RB31101
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:500. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- FCN3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))
- Autre désignation
- FCN3 (FCN3 Produits)
- Synonymes
- anticorps FCNH, anticorps HAKA1, anticorps ficolin 3, anticorps ficolin-3, anticorps FCN3, anticorps Fcn3, anticorps fcn3-A
- Sujet
- Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
- Poids moléculaire
- 32903
- ID gène
- 8547
- NCBI Accession
- NP_003656, NP_775628
- UniProt
- O75636
- Pathways
- Système du Complément
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