P4HB anticorps

N° du produit ABIN6566647

Détail du produit anti-P4HB anticorps

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant protein of human P4HB

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IF 1:20 - 1:100 IP 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur P4HB

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Autre désignation: P4HB (P4HB Produits)

Synonymes: anticorps DSI, anticorps ERBA2L, anticorps GIT, anticorps P4Hbeta, anticorps PDI, anticorps PDIA1, anticorps PHDB, anticorps PO4DB, anticorps PO4HB, anticorps PROHB, anticorps PDA2, anticorps PDIP, anticorps PDIR, anticorps ERp59, anticorps Pdia1, anticorps Thbp, anticorps p55, anticorps XPDIp, anticorps pdi, anticorps 1810041F13Rik, anticorps AI661267, anticorps Pdip, anticorps Pdipl, anticorps p58, anticorps prolyl 4-hydroxylase subunit beta, anticorps protein disulfide isomerase family A member 2, anticorps prolyl 4-hydroxylase, beta polypeptide, anticorps protein disulfide isomerase family A member 2 L homeolog, anticorps protein disulfide isomerase associated 2, anticorps prolyl 4-hydroxylase subunit beta L homeolog, anticorps protein disulfide-isomerase, anticorps P4HB, anticorps PDIA2, anticorps P4hb, anticorps pdia2.L, anticorps Pdia2, anticorps p4hb.L, anticorps LOC8281065

Sujet:

Synonyms: Cellular thyroid hormone binding protein,Cellular thyroid hormone-binding protein,Collagen prolyl 4 hydroxylase beta,Disulphide Isomerase,DSI,EC 5.3.4.1,Endoplasmic reticulum resident protein 59,ER protein 59,ERBA2L,ERp59,GIT,Gltathione insulin transhydrogenase,Glutathione insulin transhydrogenase,P4HB,P4Hbeta,p55,PDI,PDIA1,PDIA1,PDIR,PHDB,PO4DB,PO4HB,Procollagen proline 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase) beta polypeptide (protein disulfide isomerase associated 1),Procollagen proline 2 oxoglutarate 4 dioxygenase beta subunit,PROHB,Prolyl 4 hydroxylase beta polypeptide,Prolyl 4 hydroxylase beta subunit,Prolyl 4 hydroxylase subunit beta,Prolyl 4-hydroxylase subunit beta,Protein disulfide isomerase associated 1,Protein disulfide isomerase,family A,member 1,Protein disulfide isomerase/oxidoreductase,Protein disulfide-isomerase,Protocollagen hydroxylase,Thbp,Thyroid hormone binding protein p55,Thyroid hormone binding protein p55 cellular,V erb a avian erythroblastic leukemia viral oncogene homolog 2 like

Background: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Poids moléculaire:

Observed_MW: 57kDa

Calculated_MW: 57kDa

ID gène: 5034

UniProt: P07237

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism