CRADD anticorps
-
- Antigène Voir toutes CRADD Anticorps
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CRADD est non-conjugé
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human CRADD (NP_003796.1).
- Isotype
- IgG
- Top Product
- Discover our top product CRADD Anticorps primaire
-
-
- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
- Autre désignation
- CRADD (CRADD Produits)
- Synonymes
- anticorps cradd, anticorps MGC89035, anticorps zgc:101717, anticorps CRADD, anticorps DKFZp468A2219, anticorps LOC100226369, anticorps raidd, anticorps MGC78788, anticorps MRT34, anticorps RAIDD, anticorps CASP2 and RIPK1 domain containing adaptor with death domain, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 1, anticorps CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog, anticorps CRADD, anticorps cradd.1, anticorps cradd, anticorps cradd.2.S, anticorps Cradd
- Sujet
- This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
-
Observed_MW: 22kDa
Calculated_MW: 11kDa/22kDa
- ID gène
- 8738
- UniProt
- P78560
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
-