IBTK anticorps
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- Antigène Voir toutes IBTK Anticorps
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IBTK est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human IBTK
- Isotype
- IgG
- Top Product
- Discover our top product IBTK Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
- Autre désignation
- IBTK (IBTK Produits)
- Synonymes
- anticorps IBTK, anticorps fi40c08, anticorps wu:fi40c08, anticorps DKFZp468J085, anticorps BTBD26, anticorps BTKI, anticorps RP1-93K22.1, anticorps 5430411K16Rik, anticorps AA409502, anticorps mKIAA1417, anticorps inhibitor of Bruton tyrosine kinase, anticorps inhibitor of Bruton agammaglobulinemia tyrosine kinase, anticorps inhibitor of Bruton tyrosine kinase L homeolog, anticorps IBTK, anticorps ibtk, anticorps Ibtk, anticorps ibtk.L
- Sujet
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Synonyms: BTKI,IBtk,IBTK,inhibitor of Bruton agammaglobulinemia tyrosine kinase,Inhibitor of Bruton tyrosine kinase
Background: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Poids moléculaire
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Observed_MW: 167kDa
Calculated_MW: 26kDa/133kDa/150kDa
- ID gène
- 25998
- UniProt
- Q9P2D0
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