IBTK anticorps

N° du produit ABIN6568506

Détail du produit anti-IBTK anticorps

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IBTK est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human IBTK

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IBTK

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Autre désignation: IBTK (IBTK Produits)

Synonymes: anticorps IBTK, anticorps fi40c08, anticorps wu:fi40c08, anticorps DKFZp468J085, anticorps BTBD26, anticorps BTKI, anticorps RP1-93K22.1, anticorps 5430411K16Rik, anticorps AA409502, anticorps mKIAA1417, anticorps inhibitor of Bruton tyrosine kinase, anticorps inhibitor of Bruton agammaglobulinemia tyrosine kinase, anticorps inhibitor of Bruton tyrosine kinase L homeolog, anticorps IBTK, anticorps ibtk, anticorps Ibtk, anticorps ibtk.L

Sujet:

Synonyms: BTKI,IBtk,IBTK,inhibitor of Bruton agammaglobulinemia tyrosine kinase,Inhibitor of Bruton tyrosine kinase

Background: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 167kDa

Calculated_MW: 26kDa/133kDa/150kDa

ID gène: 25998

UniProt: Q9P2D0