GRAP anticorps

N° du produit ABIN6568682

Détail du produit anti-GRAP anticorps

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAP est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GRAP (NP_006604.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GRAP

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Autre désignation: GRAP (GRAP Produits)

Synonymes: anticorps 8430435N19Rik, anticorps BB233594, anticorps GRAP, anticorps grap, anticorps zgc:110202, anticorps MGC109892, anticorps si:dkeyp-9d4.1, anticorps Grap, anticorps GRB2-related adaptor protein, anticorps GRB2-related adapter protein, anticorps GRB2-related adaptor protein a, anticorps GRB2-related adaptor protein b, anticorps GRAP, anticorps Grap, anticorps LOC489534, anticorps grapa, anticorps grapb, anticorps LOC100727005

Sujet: GRAP,This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Poids moléculaire:

Observed_MW: 36kDa

Calculated_MW: 25kDa

ID gène: 10750

UniProt: Q13588