FANCI anticorps

N° du produit ABIN6569525

Détail du produit anti-FANCI anticorps

Antigène: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCI est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human FANCI

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FANCI

Antigène: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Autre désignation: FANCI (FANCI Produits)

Synonymes: anticorps KIAA1794, anticorps Fanconi anemia complementation group I, anticorps Fanconi anemia, complementation group I, anticorps FANCI, anticorps Fanci

Sujet:

Synonyms: FANCI,FANCI gene,FANCI,Fanconi anemia group I protein,Fanconi anemia, complementation group I,FLJ10719,FLJ14658,KIAA1794,Protein FACI,Protein FANCI

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 170kDa

Calculated_MW: 27kDa/142kDa/149kDa

ID gène: 55215

UniProt: Q9NVI1

Pathways: Réparation de l'ADN