Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.
anticorps KV11.1, anticorps Kv8.2, anticorps RCD3B, anticorps potassium voltage-gated channel modifier subfamily V member 2, anticorps potassium channel, subfamily V, member 2, anticorps KCNV2, anticorps Kcnv2
Sujet
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.