AKR1C4 anticorps

N° du produit ABIN5962857

Détail du produit anti-AKR1C4 anticorps

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C4 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human AKR1C4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur AKR1C4

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Autre désignation: AKR1C4 (AKR1C4 Produits)

Synonymes: anticorps 3-alpha-HSD, anticorps C11, anticorps CDR, anticorps CHDR, anticorps DD-4, anticorps DD4, anticorps HAKRA, anticorps aldo-keto reductase family 1 member C4, anticorps AKR1C4

Sujet:

Synonyms: 3 alpha HSD1,3-alpha-HSD1,3-alpha-hydroxysteroid dehydrogenase type I,AK1C4,AKR1C4,Aldo keto reductase family 1 member C4,Aldo-keto reductase family 1 member C4,CDR,Chlordecone reductase,DD-4,DD4,Dihydrodiol dehydrogenase 4,HAKRA

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Poids moléculaire:

Observed_MW: 37kDa

Calculated_MW: 37kDa

ID gène: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis