ABCC2 anticorps

N° du produit ABIN5965180

Détail du produit anti-ABCC2 anticorps

Antigène: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC2 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human ABCC2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ABCC2

Antigène: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Autre désignation: ABCC2 (ABCC2 Produits)

Synonymes: anticorps ABC30, anticorps CMOAT, anticorps DJS, anticorps MRP2, anticorps cMRP, anticorps AI173996, anticorps Abc30, anticorps Cmoat, anticorps Mrp2, anticorps ATP binding cassette subfamily C member 2, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 2, anticorps ABCC2, anticorps Abcc2

Sujet:

Synonyms: ABC30,abcC2,ATP binding cassette sub family C (CFTR/MRP) member 2,ATP binding cassette subfamily C member 2,ATP-binding cassette sub-family C member 2,Canalicular multidrug resistance protein,Canalicular multispecific organic anion transporter 1,CMOAT,CMOAT1,cMRP,DJS,KIAA1010,MRP 2,MRP2,Multidrug resistance associated protein 2,Multidrug resistance-associated protein 2

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine, therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.

Poids moléculaire:

Observed_MW: 344kDa

Calculated_MW: 174kDa

ID gène: 1244

UniProt: Q92887

Pathways: Hormone Transport