TNFRSF13C anticorps (N-Term)

N° du produit ABIN657960

Détail du produit anti-TNFRSF13C anticorps

Antigène: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF13C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TNFRSF13C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNFRSF13C.

Clone: RB34078

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TNFRSF13C Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur TNFRSF13C

Antigène: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Autre désignation: TNFRSF13C (TNFRSF13C Produits)

Synonymes: anticorps RGD1560810, anticorps TNFRSF13C, anticorps BAFF-R, anticorps BAFFR, anticorps BROMIX, anticorps CD268, anticorps CVID4, anticorps prolixin, anticorps 2010006P15Rik, anticorps Baffr, anticorps Bcmd, anticorps Bcmd-1, anticorps Bcmd1, anticorps Lvis22, anticorps TNF receptor superfamily member 13C, anticorps uncharacterized LOC746611, anticorps tumor necrosis factor receptor superfamily, member 13c, anticorps TNFRSF13C, anticorps Tnfrsf13c, anticorps LOC746611

Sujet: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Poids moléculaire: 18864

ID gène: 115650

NCBI Accession: NP_443177

UniProt: Q96RJ3

Pathways: Signalisation NF-kappaB