TNFRSF13C anticorps

N° du produit ABIN6939146

Détail du produit anti-TNFRSF13C anticorps

Antigène: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF13C est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Immunogène: Recombinant full-length human CD268 protein

Clone: BAFFR-1557

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Raji cells. Tonsil and lymph node.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TNFRSF13C

Antigène: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Autre désignation: TNFRSF13C (TNFRSF13C Produits)

Synonymes: anticorps RGD1560810, anticorps TNFRSF13C, anticorps BAFF-R, anticorps BAFFR, anticorps BROMIX, anticorps CD268, anticorps CVID4, anticorps prolixin, anticorps 2010006P15Rik, anticorps Baffr, anticorps Bcmd, anticorps Bcmd-1, anticorps Bcmd1, anticorps Lvis22, anticorps TNF receptor superfamily member 13C, anticorps uncharacterized LOC746611, anticorps tumor necrosis factor receptor superfamily, member 13c, anticorps TNFRSF13C, anticorps Tnfrsf13c, anticorps LOC746611

Sujet: Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494], also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins, the numbers of circulating B cells is usually in the normal range, but can be low.

Poids moléculaire: 19kDa (Monomer), 40kDa (Dimer)

ID gène: 115650

UniProt: Q96RJ3

Pathways: Signalisation NF-kappaB