TLN1 anticorps

N° du produit ABIN6654085

Détail du produit anti-TLN1 anticorps

Antigène: TLN1 (Talin 1 (TLN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: Amino acids QQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQ were used as the immunogen for the Talin 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Talin 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Talin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur TLN1

Antigène: TLN1 (Talin 1 (TLN1))

Autre désignation: Talin 1 (TLN1 Produits)

Synonymes: anticorps ILWEQ, anticorps TLN, anticorps Tln, anticorps sb:cb854, anticorps wu:fb05c02, anticorps TLN1, anticorps talin-1, anticorps tln, anticorps talin 1, anticorps talin 1 L homeolog, anticorps Talin 1, anticorps talin-1, anticorps TLN1, anticorps Tln1, anticorps tln1, anticorps tln1.L, anticorps Bm1_56490, anticorps LOC100380665

Sujet: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location