RP2 anticorps (AA 244-348)

N° du produit ABIN6654138

Détail du produit anti-RP2 anticorps

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Épitope: AA 244-348

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: Amino acids D244-M348 from the human protein were used as the immunogen for the RP2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RP2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RP2

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Autre désignation: RP2 / XRP2 (RP2 Produits)

Synonymes: anticorps Rp2h, anticorps RGD1565124, anticorps RP2, anticorps wu:fj10e02, anticorps wu:fm72d05, anticorps zfrp2, anticorps zgc:55632, anticorps DELXp11.3, anticorps NM23-H10, anticorps NME10, anticorps TBCCD2, anticorps XRP2, anticorps AI662636, anticorps Rp2, anticorps RP2, ARL3 GTPase activating protein, anticorps XRP2 protein, anticorps XRP2-like protein, anticorps retinitis pigmentosa 2 (X-linked recessive), anticorps RP2, ARL3 GTPase activating protein S homeolog, anticorps retinitis pigmentosa 2 homolog, anticorps Rp2, anticorps RP2, anticorps Bm1_36735, anticorps PITG_13367, anticorps LOAG_11813, anticorps rp2, anticorps rp2.S

Sujet: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process