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CD22 anticorps (AA 52-178)

CD22 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal BLCAM-1795 unconjugated
N° du produit ABIN6654734
  • Antigène Voir toutes CD22 Anticorps
    CD22 (CD22 Molecule (CD22))
    Épitope
    • 16
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-178
    Reactivité
    • 154
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 101
    • 62
    • 14
    Souris
    Clonalité
    • 125
    • 54
    Monoclonal
    Conjugué
    • 82
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD22 est non-conjugé
    Application
    • 112
    • 71
    • 46
    • 39
    • 38
    • 19
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Purified
    Pureté
    Protein G affinity chromatography
    Immunogène
    Amino acids 52-178 from the human protein were used as the immunogen for the CD22 antibody.
    Clone
    BLCAM-1795
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD22 Anticorps primaire
  • Indications d'application
    Optimal dilution of the CD22 antibody should be determined by the researcher.\. ELISA: 2-4 μg/mL (order BSA free formulation for coating),Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the CD22 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    CD22 (CD22 Molecule (CD22))
    Autre désignation
    CD22 (CD22 Produits)
    Synonymes
    anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
    Sujet
    Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
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