CD22 anticorps (AA 52-178)
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- Antigène Voir toutes CD22 Anticorps
- CD22 (CD22 Molecule (CD22))
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Épitope
- AA 52-178
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD22 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Purified
- Pureté
- Protein G affinity chromatography
- Immunogène
- Amino acids 52-178 from the human protein were used as the immunogen for the CD22 antibody.
- Clone
- BLCAM-1795
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD22 Anticorps primaire
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- Indications d'application
- Optimal dilution of the CD22 antibody should be determined by the researcher.\. ELISA: 2-4 μg/mL (order BSA free formulation for coating),Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
- Restrictions
- For Research Use only
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- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the CD22 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- CD22 (CD22 Molecule (CD22))
- Autre désignation
- CD22 (CD22 Produits)
- Synonymes
- anticorps A530093D23, anticorps Lyb-8, anticorps Lyb8, anticorps SIGLEC-2, anticorps SIGLEC2, anticorps siglec-2, anticorps CD22 antigen, anticorps CD22 molecule, anticorps Cd22, anticorps CD22
- Sujet
- Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
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