TRPM7 anticorps (C-Term)

N° du produit ABIN6657588

Détail du produit anti-TRPM7 anticorps

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Épitope: C-Term

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRPM7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Réactivité croisée: Humain

Purification: Anti-TRPM7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with TRPM7 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against TrpM6. Cross-reactivity with TRPM7 from other sources has not been determined. Channels and Transporters research.

Immunogène:

Immunogen: TRPM7 Antibody was produced in mice by repeated immunizations raised against a fusion proteins corresponding to the c-terminus region of mouse TrpM7.

Immunogen Type: Peptide

Clone: S74-25

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 1:1000

Application Note: Anti-TRPM7 Antibody is suitable for use in WB, IHC, and IF microscopy. Expect a band approximately ~220 kDa on specific lysates, in extracts of cells transiently transfected with TrpM7. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1:1000

IF Microscopy Dilution: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur TRPM7

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Autre désignation: TRPM7 (TRPM7 Produits)

Synonymes: anticorps cb495, anticorps TRPM7, anticorps chak, anticorps chak1, anticorps ltrpc7, anticorps trp-plik, anticorps ALSPDC, anticorps CHAK, anticorps CHAK1, anticorps LTRPC7, anticorps TRP-PLIK, anticorps 2310022G15Rik, anticorps 4833414K03Rik, anticorps 5033407O22Rik, anticorps LTrpC-7, anticorps Ltpr7, anticorps Ltrpc7, anticorps TRPPLIK, anticorps Chak, anticorps Trp-plik, anticorps transient receptor potential cation channel subfamily M member 7, anticorps transient receptor potential cation channel, subfamily M, member 7, anticorps TRPM7, anticorps trpm7, anticorps Trpm7

Sujet:

Synonyms: CHAK antibody, CHAK1 antibody, LTRPC7 antibody, TRP PLIK antibody, Channel kinase 1 antibody, Transient receptor potential cation channel subfamily M member 7 antibody, Channel-kinase 1 antibody, Long transient receptor potential channel 7 antibody, LTrpC-7 antibody, Transient receptor potential-phospholipase C-interacting kinase antibody, TRP-PLIK antibody, Trpm7 antibody

Background: TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.

Gene Name: Trpm7

ID gène: 58800

NCBI Accession: NP_001157797

UniProt: Q923J1