NR2C1 anticorps (N-Term)

N° du produit ABIN6657689

Détail du produit anti-NR2C1 anticorps

Antigène: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Épitope: N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2C1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-TR2 antibody is directed against mouse Testicular Receptor 2 protein. Anti-TR2 antibody is provided as monospecific neat serum. Reactivity is expected against human and rat.

Immunogène:

Immunogen: Anti-TR2 Antibody was produced in rabbit by repeated immunizations with TR2 fusion protein from the N-terminal region of the Testicular Receptor 2 protein.

Immunogen Type: Recombinant Protein

Information d'application

Indications d'application:

Application Note: Anti-Testicular Receptor 2 (Rabbit) antibody is suitable for use in Western Blots. Anti-Testicular Receptor 2 antibodies are specific for the ~64 kDa TR2 protein in Western blots of testes and nuclear extracts from MEL cell lines. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur NR2C1

Antigène: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Autre désignation: Testicular Receptor 2 (TR2) (NR2C1 Produits)

Synonymes: anticorps TR2, anticorps NR2C1, anticorps dor2, anticorps tr2-11, anticorps xDOR2, anticorps DKFZp468M0512, anticorps si:dkey-183c16.2, anticorps zgc:110672, anticorps 4831444H07Rik, anticorps 80.3, anticorps Eenr, anticorps Tr2-11, anticorps Tr2, anticorps Psg4, anticorps TR2-11, anticorps PSG9, anticorps nr2c1, anticorps nuclear receptor subfamily 2 group C member 1, anticorps nuclear receptor subfamily 2 group C member 1 S homeolog, anticorps nuclear receptor subfamily 2, group C, member 1, anticorps pregnancy specific beta-1-glycoprotein 4, anticorps nuclear receptor subfamily 2 group C member 1 L homeolog, anticorps NR2C1, anticorps nr2c1.S, anticorps nr2c1, anticorps Nr2c1, anticorps PSG4, anticorps nr2c1.L

Sujet:

Synonyms: Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, mTR2

Background: TR2 antibody detects Testicular receptor 2 (TR2), which is a member of the orphan nuclear receptor family. It is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA directly interacting with HDAC3 and HDAC4 via DNA-binding domains. TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands. In addition, TR2 has recently been shown to form a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression. Anti-TR2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Stem Cell research.

Gene Name: NR2C1

ID gène: 22025

UniProt: Q505F1

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway