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PD-L1 anticorps

PD-L1 Reactivité: Souris FACS Hôte: Rat Monoclonal 10F-9G2 unconjugated
N° du produit ABIN6727404
  • Antigène Voir toutes PD-L1 Anticorps
    PD-L1 (CD274 (PD-L1))
    Reactivité
    • 171
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Souris
    Hôte
    • 127
    • 62
    • 17
    • 4
    • 4
    • 1
    Rat
    Clonalité
    • 108
    • 105
    • 2
    Monoclonal
    Conjugué
    • 99
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp PD-L1 est non-conjugé
    Application
    • 139
    • 104
    • 60
    • 40
    • 38
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Purified
    Clone
    10F-9G2
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Matching Isotype Control: Purified Rat IgG2b, κ Isotype Control (ABIN7469856)

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2~8°C. Do not freeze.
  • Antigène
    PD-L1 (CD274 (PD-L1))
    Autre désignation
    CD274/PD-L1 (PD-L1 Produits)
    Synonymes
    anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2
    Sujet
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
    ID gène
    60533
    UniProt
    Q9EP73
    Pathways
    Cancer Immune Checkpoints
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