Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Gel Shift (GS)
Specificité
Recognizes p43 phosphorylated CREB. May also recognize p30 and p38kD proteins. The p30 & p38 proteins may be phosphorylated CREM and ATF-1 respectively, since the two proteins share significant homology to the phosphorylated CREB immunizing peptide. Species cross-reactivity: Rat, mouse, human and hamster.
Réactivité croisée
Hamster, Humain, Souris
Homologie
Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Dog, Rabbit, Pig, Turkey, Chicken, Lizard, Xenopus, Salmon, Stickleback, Pufferfish, Zebrafish (100%).
Purification
Protein A Column
Immunogène
Synthetic phosphopeptide corresponding to residues 123-136 [KRREILSRRP(pS)Y-RK] of rat CREB (cAMP response element binding protein) coupled to keyhole limpet hemocyanin (KLH).