CYLD anticorps (N-Term)
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- Antigène Voir toutes CYLD Anticorps
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYLD est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- Human CYLD
- Purification
- Protein A purified
- Immunogène
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A recombinant protein fragment from the N-terminal region of human CYLD.
Type of Immunogen: Recombinant protein - Isotype
- IgG
- Top Product
- Discover our top product CYLD Anticorps primaire
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- Indications d'application
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Approved: WB (2 - 5 μg/mL)
Usage: CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- avoid freeze thaw cycles
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze-thaw cycles.
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- Antigène
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Autre désignation
- CYLD (CYLD Produits)
- Synonymes
- anticorps BRSS, anticorps CDMT, anticorps CYLD1, anticorps CYLDI, anticorps EAC, anticorps MFT, anticorps MFT1, anticorps SBS, anticorps TEM, anticorps USPL2, anticorps 2010013M14Rik, anticorps 2900009M21Rik, anticorps C130039D01Rik, anticorps mKIAA0849, anticorps cyld, anticorps LRRGT00003, anticorps Rp1, anticorps Rp1h, anticorps CYLD lysine 63 deubiquitinase, anticorps cylindromatosis (turban tumor syndrome), a, anticorps CYLD, anticorps Cyld, anticorps cylda
- Sujet
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Name/Gene ID: CYLD
Synonyms: CYLD, CDMT, Deubiquitinating enzyme CYLD, CYLDI, EAC, HSPC057, MFT1, MFT, SBS, TEM, BRSS, Ubiquitin thiolesterase CYLD, USPL2, CYLD1, KIAA0849, Ubiquitin thioesterase CYLD - ID gène
- 1540
- Pathways
- Apoptose, Activation of Innate immune Response
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